Comprehensive Immune System Support

NHR Science Advance Immune Support (AIS) Combo is a comprehensive arsenal of immune-supportive powerful herbs,
helping the body maintain a strong defense, and help supports seasonal immune health. AIS Combo–is a toolkit of three
clinically studied dietary supplements: Organic Elderberry Extract, Organic Paractin® Andrographis paniculate extract, and
Adapticort® Eurycoma longifolia extract, selected for their abilities to support the body’s overall immune response,
encourage timely immune cell response, help defend the body in the face of cold-weather challenges, and fortify your
immune system to empower good health through all seasons.*

Benefits of Advance Immune Support Pack

is a comprehensive arsenal of immune-supportive powerful herbs, helping the body maintain a strong defense, and help supports seasonal immune health. Products that comprise in this combo packs were selected for their abilities to support the body’s overall immune response, encourage timely immune cell response, and help defend the body in the face of cold-weather challenges.  The clinically studied ingredients have been shown to provide the following benefits:

Healthy Benefits

Optimize Respiratory Function

Supports Immune System

Organic Clinically Researched Herb Formula

Powerful Antioxidant Activity

Promotes Youthful Immunity


ParActin® Immune Organic Andrographis Paniculata Extract
(50% Andrographolide)

ParActin® is a patented extract from Andrographis paniculata, standardized to 50% andrographolide. ParActin® works by inhibiting NF-kB – the master switch of the human immune and inflammatory response system. There are many published studies on the immune-support mechanisms of action of andrographolide: it inhibits a pathogenic agent’s protein synthesis and expression, inhibits it from entering inside the cell wall, inhibits the agent’s DNA replications; reduces the agent’s receptor signaling, & decreases ACE2 expression. Three double-blind, placebo-controlled studies has shown Andrographis to significantly improve certain immune indicators, and optimize immune &  inflammatory response starting at day two, helping to defend the body in the face of cold-weather challenges.* 

Click here to learn more about Andrographis

Benefits of Organic ParActin® Andrographis Extract:

ElderberryCare™ Organic Elderberry 12:1 Extract

Elderberry is high in anthocyanins and polyphenols, providing superior antioxidant protection to support healthy immune response and helps protect from free radical damage and airborne elements.* ElderberryCare™ Sambucus Nigra Berry Extract is 12 times the concentration of regular Elderberry. Each 1g serving is equivalent to 12g of elderberry fruits, sweetened only with organic monk fruit extract.  New clinical and pre-clinical research shows that standardized elderberry extract supports your immune system during stress, travel, and seasonal changes.*    

Click here to learn more about Elderberry

Benefits of Organic ElderberryCare™ Extract:

Adapticort® Wild Harvested Eurycoma longifolia 100:1 Extract

Adapticort® is a patented extract from Eurycoma longifolia, standardized to 40% glyco saponins and 22% Eurypeptides.  Cortisol is a stress hormone that promotes immune senescence (aging immune system).  Backed by several double blind, placebo control human trials, Adapticort® supports healthy cortisol level, promotes youthful immune response by stimulating immune cell function and other immune factors that serve as your body’s first line of defense.*

Click here to learn more about Eurycoma

Benefits of Adapticort® Eurycoma Longifolia Extract:

Advanced Immune Support Pack is Clinically Proven to Promote Proper Immunity, Respiratory & Lung Function.*

Advance Immune Pack

The natural way to support seasonal immune health

Your body’s immune system is your natural protection against harmful invaders.  Immune cells are like security guards. They say who’s in, who’s out and who’s banned.  Aging and other environmental stressors (due to excess inflammation, toxins, and stress) all contribute to a decline in our immune function. As you grow older, your immune system does not work as well, your body may heal more slowly, and the immune system’s ability to detect and defend your body also declines.


Discover how YOU can help boost your immune power, enhance your resilience, and nourish your defense system.

Your immune system is mostly invisible to you but it is your fortress of good health. It is deeply complex, a coordinated orchestra of organs, tissues and cells that focus on detecting potential evildoers – pathogens such as viruses, fungi, yeasts and certain bacteria, then coordinating a response to disarm them and get rid of them.

Your Immune System's Level 1: BARRIERS

Skin and Cilia prevent invaders from entering


Level 1 defense is the first point of contact barriers such as skin and cilia (tiny hairs in your nasal passages and lungs that brushes out or captures unwelcome agents.  If level 1 fails and invaders slips through, level 2 innate immune defense kicks in.  

Your Immune System's Level 2: INNATE

These cells and chemicals stop invaders from spreading

Level 2 immune defense comprises of a complex network of cells and proteins that defends your body against invaders.  When an invader gets in, your body’s innate immune cells and chemicals get on the scene fast – a lot like first responders in real life. They love to fight and they prevent the spread of invaders in the body.  

These innate immune cells includes: 

These immune cells include those that send signals for help (cytokines) and those that destroy the invaders (natural killer cells, scavengers such as neutrophils and macrophages, and defensins).  If these cells don’t do the trick and the invader remains elusive to run amok, level 3 adaptive immune defense steps in.  

Your Immune System's Level 3: ADAPTIVE

Blood Warriors (with a grudge) attack invaders

Level 3 is known as adaptive or acquired immunity. They consists of cells, notably antibodies, your stored immune memory of past occurrence, that have become specialized in identifying previous invasive agents and are trained to destroy agents quickly if invaders enters the body again.  Antibodies are part of that response and help your body respond to the same invader much faster if you encounter it again.  Some antibodies have a long-lasting effects and are called “memory” antibodies. 

Your immune system fights infections using organs, cells and proteins that work together in a highly coordinated dance. Healthy eating, good nutrition, less stress, good sleeping habit and regular physical activity make your immune system stronger and can help you support your immune system.

AGING & Immune

Aging and other environmental stressors (due to excess inflammation, toxins, and stress) all contribute to a decline in our immune function. As you grow older, your immune system does not work as well, leaving us increasingly susceptible to health threats.   Your body may heal more slowly as there are fewer immune cells in the body to bring about healing.  The immune system’s ability to detect and correct cell defects also declines.  In addition, immune cell diversity also declines, reducing our body’s immune defense.  This process is called immune senescence.

The following immune system changes may occur:

Decline in Naïve T Cells

Naïve T cells are inexperience T cells that can easily be activated to recognize and respond to new challenges.  There is a general decrease in naïve T cells after roughly age 70.   As a result, our immune system becomes slower to respond and this increases our risk of getting sick.

Increasing Numbers of Senescent Memory T cells 

Memory T cells are your stored immune memory of past occurrence that are trained to destroy invaders if they enter the body again.  Our body’s pool of protective memory T cells increase over time.

Decreased in Functional Natural Killer (NK) Cell Activity

High NK cell activity is associated with longevity and healthy aging, while reduced NK cell function is linked to increased health imbalances.  NK cell function decreases with age, generating fewer immune-regulating cytokines.

Overproduction of Cytokines

 Immune senescence is associated with high levels of the inflammatory cytokine interleukin-6 (IL-6).  In the elderly, elevated IL-6 is associated with many health challenges.

Immune Support Botanicals

Exercise helps boost your immune system.  Regular moderate-intensity exercise can strengthen resistance to invaders and improve immune system function.  Several human studies have indicated that moderate exercise may combat immune senescence.

Chronic stress diminishes our immune function and dysregulate our innate and adaptive immune responses. Studies had shown cortisol (stress hormone) to contribute to immune senescence.  In fact, the ratio of cortisol to dehydroepiandrosterone (DHEA), may be an important determinant of immune senescence.

Sleep deprivation is associated with elevated cortisol levels, as well as higher daytime levels of inflammatory cytokines including IL-1, IL-6, and tumor necrosis factor-alpha.  The adverse effects of poor sleep include functional changes in regulatory T cells and other cells of the adaptive immune system, as well as reduced numbers of NK cells and T and B cells.  Adequate sleep may help improve immune function.

The goal of caloric restriction is to reduce total caloric intake while maintaining optimal nutrition. Eat healthy foods primarily composed of low-calorie, nutrient-dense foods such as vegetables, fruits, legumes, nuts and seeds, and whole grains; limiting intake of animal products; and avoiding calorie-dense, nutrient-poor foods.  Calorie restriction in animals has been shown to prolong lifespan and delay aging, and to confer a more youthful T-cell profile.  Good nutrition keeps your immune system strong.

DO NOT smoke. Smoking weakens your immune system.

Limit your intake of alcohol. Ask your provider how much alcohol is safe for you.

Botanicals to Support Immune health


Eurycoma Longifolia (EL), comes from the lush rainforest of Southeast Asia. The roots of EL have traditionally been used as a tonic, energy enhancer, and adaptogen. Adapticort is a patended extract from Eurycoma longifolia, Clinical studies has shows Adapticort to promotes healthy cortisol level, imporve immune response by stimulating immune cell development & activity*.

In a randomized, double-blind placebo-controlled clinical trial with 63 subjects with moderate stress, 200mg of Adapticort daily for 4 weeks were able to improve overall mood state, and improved cortisol – 16%*

In a 2016 randomized placebo controld study, 84 middle aged individual with low Scoring of Immunological Vigor (SIV)


Elderberry is primarily found in Europe and North America.  Black Elderberries have long been used in traditional cultures to support immune function. Elderberry has an extensive history of being used during seasonal immune challenges. Regarded as an “Elder” plant in Native American Herbalism, Elderberry has been used collectively by many tribes as a tonic medicine and food to promote health and vitality.

In a randomized, double-blind placebo-controlled clinical trial of 312 economy class passengers travelling internationally, supplementation of edelberry supplement encourage timely immune cell response and supports the body to maintain a strong defense during stressful intercontinental air travel*

In another randomized, double-blind, placebo-controlled study during the influenza season of 1999 – 2000 in Norway, 60 volunteers received 15 ml of elderberry pf placebo syrup four times a day for 5 days. Supplementation of eldelberry help support immune function during seasonal immune challenges*


Andrographis Paniculata has traditionally been used in Indian and Chinese herbal medicine to support seasonal immune health.  There are currently 33 published research of randomized controlled trials (7175 patients) either using Andrographis as a monotherapy and as herbal mixture, showing Andrographis to be effective in supporting the body’s overall immune response to help defend the body in the face of cold-weather challenges.

Clinically Effective Immunity Ingredients That Actually Make a Difference

A medicine cabinet essential to help support healthy immune response especially during winter* 

Advance Immune Support Pack combines clinically studied dosages of three powerful, immune-support ingredients shown to encourage immune cells to respond in a timely manner, to promote effective respiratory & Lung function*

Winter Immune Support Essential

Customer Review



I am glad I found these products. I’ve noticed my energy level has increased, I sleep better, and my overall well-being seems to have gotten better as I've been taking it regularly. I highly recommend it. - Vicky


Love it! At a time like this, I take it everyday for prevention. Each time I feel a little scratchy throat, I double up on these and feel much better! - Robert


A product that works from a company that’s into research. Wow, this is actually a company that is dedicated to research. I love to see natural products that are backed by science and I applaud their efforts. I take Immune Protect as my first line of defense, and I like that the ingredients are certified organic too. I am going to continue to make my immune systems as strong as they can be and I love this product. - Phillip


I like that all the ingredients in Immune Protect are certified organic. I love the convenience of monthly shipment with automatic refill so I don’t have to worry about running out. - Mary Jane

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


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